Ribonuclease S redux.

نویسندگان

  • Rex W Watkins
  • Ulrich Arnold
  • Ronald T Raines
چکیده

The S-peptide and S-protein components of bovine pancreatic ribonuclease form a noncovalent complex with restored ribonucleolytic activity. Although this archetypal protein-fragment complementation system has been the object of historic work in protein chemistry, intrinsic limitations compromise its utility. Modern methods are shown to overcome those limitations and enable new applications.

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عنوان ژورنال:
  • Chemical communications

دوره 47 3  شماره 

صفحات  -

تاریخ انتشار 2011